PLOS Biology<p>Current methods for profiling <a href="https://fediscience.org/tags/HistoneModifications" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>HistoneModifications</span></a> require cell isolation &amp; don't work with all tissue types. <span class="h-card" translate="no"><a href="https://bird.makeup/users/jellevda" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>jellevda</span></a></span> &amp;co adapt Targeted DamID (TaDa) to profile cell-type-specific <a href="https://fediscience.org/tags/histone" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>histone</span></a> marks throughout the genome, in vivo, without cell isolation <a href="https://fediscience.org/tags/plosbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>plosbiology</span></a> <a href="https://plos.io/3Dw8sUD" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3Dw8sUD</span><span class="invisible"></span></a></p>