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#modifications

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→ Une #intelligence #artificielle libre est-elle possible ?
linuxfr.org/news/une-intellige

« Posons-nous un instant la question : qu’est-ce que le #code #source d’un réseau de #neurones ? […] La #GPL fournit une définition : le code source est la forme de l’œuvre privilégiée pour effectuer des #modifications. Dans cette acception, le code source d’un réseau de neurones serait l’#algorithme d’entraînement, le réseau de neurones de départ et le #corpus sur lequel le réseau a été entraîné »

linuxfr.orgUne intelligence artificielle libre est-elle possible ? - LinuxFr.orgL’actualité du logiciel libre et des sujets voisins (DIY, Open Hardware, Open Data, les Communs, etc.), sur un site francophone contributif géré par une équipe bénévole par et pour des libristes enthousiastes

#Elephants eat by bringing their food to their #mouths using their trunks. But that only works #sideways. An evolutionary adaptation to the fact that the #trunk, as an extended nose and at the same time a highly innervated, precise #grippingorgan, is connected to further skull #modifications, even the arrangement of mouth #vibrissae. There are also left-wing and right-wing “drunkers,” as scientists have recently discovered.
© #StefanFWirth Berlin 2024

My #blogarticle:
x.com/wirthstef/status/1829163

Something different today.

I got a drill-press jig for my dremel that allows me to drill straight holes through things.
This is good enough in itself.

It also allows you to mount the dremel sideways...

but, there's no included surface for keeping things straight when sideways.

So I made one.

It can adjust up and down with the dremel, and can move towards and away from the dremel.

And it includes a sled for moving things under the tool.

#introduction I am a molecular and structural biologist working at the Institute of Physico-Chemical Biology in Paris. I am working with proteins and RNAs, fascinated by the many ways they interact with eachother. I use all sorts of biophysical techniques and molecular tools, but mostly #NMR and #Crystallography. Special interests in #RNA maturation and post-transcriptional #modifications.

I will here post about pre-prints, articles, conferences, related to my interests in research.

We benchmarked the ability of our own basecalling models to detect #RNA #modifications using @nanopore direct RNA sequencing.

biorxiv.org/content/10.1101/20

Basecalling models are at the heart of converting the current intensity signal into a nucleotide sequence. Given this important position, we figured that by tweaking these models we could improve the detection of RNA modifications using existing tools.